pentobarbital will minimize the level or influence of nisoldipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will minimize the extent or result of lonafarnib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is a delicate CYP3A4 substrate. Coadministration with robust or moderate CYP3A4 inducers is contraindicated.
Caution when discontinuing CYP3A4 inducers which have been coadministered with hydrocodone; plasma concentrations of hydrocodone could increase and may lead to possibly lethal respiratory depression
pentobarbital will lower the extent or influence of carvedilol by influencing hepatic enzyme CYP2C9/ten metabolism. Use Warning/Monitor.
If inducer is discontinued, look at oliceridine dosage reduction and check for indications of respiratory depression.
Keep track of Carefully (one)pentobarbital will reduce the extent or influence of exemestane by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. For patients receiving exemestane with a strong CYP3A4 inducer the proposed dose of exemestane here is fifty mg each day following a meal.
pentobarbital will minimize the level or impact of oxybutynin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.
pentobarbital will decrease the level or influence of eplerenone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.
pentobarbital will minimize the extent or influence of sunitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will decrease the extent or outcome of estradiol vaginal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will lessen the extent or impact of duvelisib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration with a solid CYP3A inducer decreases duvelisib region beneath the curve (AUC), which can decrease duvelisib efficacy.
Drugs that involve prior authorization. This restriction needs that precise clinical requirements be fulfilled previous to the acceptance of the prescription.
Untimely infants are specially liable to the depressant effects of barbiturates; if barbiturates are applied all through labor and supply, resuscitation devices must be offered
pentobarbital will decrease the extent or impact of vinorelbine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Mysterious.